鄱阳湖生态经济区动漫文化创意产业发展路径研究

由于生产力信息化的变革,对文化与动漫文化产品形成的设计思维、设计方法、设计样式、传播途径与方式等提出严峻的挑战。本文就江西动漫文化产业的开发,对动漫作品、产品设计、媒介之间的产业链进行了研究与分析。     

跨文化交际与中国传统文化的导入

本文作者基于对中国传统文化课的教学及其日常与学生们的接触,在查阅了大量相关资料的基础上,论述了中国文化对培养英语专业学生跨文化交际能力的作用。从掌握中国传统文化的英文表述的必要性入手,分析了现存的问题及造成的原因,并提出了改进的可行性措施。     

A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis

To identify susceptibility loci for ankylosing spondylitis, we performed a two-stage genome-wide association study in Han Chinese. In the discovery stage, we analyzed 1,356,350 autosomal SNPs in 1,837 individuals with ankylosing spondylitis and 4,231 controls; in the validation stage, we analyzed 30 suggestive SNPs in an additional 2,100 affected individuals and 3,496 controls. We identified two new susceptibility loci between EDIL3 and HAPLN1 at 5q14.3 (rs4552569; P = 8.77 × 10(-10)) and within ANO6 at 12q12 (rs17095830; P = 1.63 × 10(-8)). We also confirmed previously reported associations in Europeans within the major histocompatibility complex (MHC) region (top SNP, rs13202464; P < 5 × 10(-324)) and at 2p15 (rs10865331; P = 1.98 × 10(-8)). We show that rs13202464 within the MHC region mainly represents the risk effect of HLA-B*27 variants (including HLA-B*2704, HLA-B*2705 and HLA-B*2715) in Chinese. The two newly discovered loci implicate genes related to bone formation and cartilage development, suggesting their potential involvement in the etiology of ankylosing spondylitis.     

VaR计算的MCMC模拟法

金融市场的快速发展使其出现了前所未有的波动性,因此金融风险监管对集体及个人都至关重要,而VaR又是现今金融风险度量的主要方法.目前常用的方法有:历史模拟法、分析法和MC模拟法,但在实施中存在很多严重的问题.文章采用MCMC模拟的方法计算VaR,并对上证指数进行实证分析,证实了MCMC比MC方法的优越性.     

Structure of the kinase domain of human RNA-dependent protein kinase with K296R mutation reveals a face-to-face dimer

RNA-dependent protein kinase (PKR) is crucial for the innate immune response, cell growth, proliferation, signal transduction and apoptosis. The activation process of PKR has been studied for many years and is still under debate. To obtain new insight into the mechanism of PKR activation, we solved the crystal structure of a latent mutant of the PKR kinase domain (PKR-KD) in the apo form at a resolution of 2.9 Å. The overall structure of PKR-KD is similar to previously reported structures. Structural analysis revealed a classical back-to-back dimer and a newly defined face-to-face dimer. Analytical ultracentrifugation experiments, electrostatic surface maps and the model of PKR-KD in complex with the eIF2α substrate all support that the face-to-face dimer is more reflective of PKR in solution. Our results provide new information on PKR dimerization and its activation mechanism.     

修辞的分类及其在各种语境中的侧重应用

修辞的应用在很大程度上可使语言显得更优雅、更形象、更富于表达力.文章主要探讨了广泛意义上修辞的分类及修辞格在不同语境中的侧重应用,并针对一些常见的语境给出了具体的例句分析.目的是切合语境选择恰当的修辞,从而提高我们的语言表达能力.     

液晶能量方程解的常边值问题

主要讨论了在星形区域中具有常边值条件的液晶能量方程的stationary解的连续结果。利用Pohozaev恒等式证明了能量方程的stationary解在整个星形区域Ω内均具有常值结果。     

采用看目标技术提高多周翻腾稳定性的研究

以实验的数据和长期训练的经验，结合跳水发展的趋势，证实了采用多次看目标技术能大大提高多周翻腾动作的准确性和稳定性。为做好打开动作创造了有利的条件，从而又大大缩短了学习高难度动作的时间，提高了质量。     

COM/CORBA互操作中的对象标识及绑定研究

随着ＣＯＭ和ＣＯＲＢＡ的迅速推广使用，用户迫切需要ＣＯＭ／ＣＯＲＢＡ互操作系统以实现ＣＯＭ和ＣＯＲＢＡ应用的集成，因此很多ＣＯＲＢＡ产品都遵照ＯＭＧ组织的ＣＯＭ／ＣＯＲＢＡ互操作规范提供了互操作的功能。然而规范中的对象标识及联编机制还存在问题，导致应用程序无法在不同的互操作系统上移植，而且在通用映射实现方式中，无法按照规范中定义的机制实现ＣＯＲＢＡ客户对ＣＯＭ对象的联编。文中提出了一种统一的对象标     

基片温度对直流电弧等离子体喷射沉积金刚石膜的影响

研究直流电弧等离子体喷射比化学气相沉积金刚石系统中，基片温度对金刚石膜生长速率和质量的影响。实验发现，金刚石膜的生长速率和结晶性随基片温度的增加而境调增加。